With broad vision of the rapid advancement in the field of microbiology, Micro-UI continuously itself to its commitment in the development and enhancement of teaching and research quality in the department. The department gained its international recognition in being appointed as a National WHO reference laboratory for influenza in the 1960s., through the intensive and fruitful research activities in influenza virus, which resulted in the identification of a new influenza virus A strain in 1957. A good networking with several laboratories in Asia and Pacific in Cholera research was also established Nationwide. Micro-UI excel itself by becoming an important partner of the Ministry of Health in the continous fight against infectious-diseases. One of the various national health programs was in eradication of cholera, with Micro-UI being appointed to escort  the Haj-Pilgrim to Saudi Arabia to overcome the cholera epidemic among the pilgrims.

Another international recognition gained by Micro-UI was through the work of Prof. H.O.K Tanzil, who did a significant effort on the research of tuberculosis. His Famous Tan Tiam Hok acid-fast-bacilli-staining, of the tuberculosis bacilli, has gained an international recognition. The leadership  of Prof. H.O.K Tanzil in Micro-UI has been continued by three outstanding Micro-UI scientists who obtained their doctoral degree under his supervision. These group of scientists then lead the advancement of the department.

In the 1970 and afterwards, young scientists were sent abroad for doctoral advancing research in the field of Microbiology, particularly in aspects related to molecular biology. Currently, Micro-UI has 19 staffs. Among them are four Professors, eight Ph.Ds, five MScs, 11 specialists in Clinical Microbiology, and four are being enrolled as Ph.D candidates. The department strongly support its staff in builnding international networking with scientists from all over the world. the current young scientists are indeed dynamically being involved in research collaborations with several national and international institutions.

In the 1980s, the national demand to develop a dengue haemorrhagic fever haemorrhagic fever (DHF) research center was urgent due to the epidemicity Dengue infection in the Indonesian population. The track record possessed by Micro-UI in Dengue  research starting in the early 1960s, was a major factor for Micro-UI to receive in five year Presidential Grant for research in DHF (1991-1995). The continous effort of Micro-UI in the medical microbiology was rewarded in 1994 with Micro-UI being chosen and identified as National center of Ecellence in Medical Microbiology, with a decree from the State Minister of Sciences and Technology No. 199/M/Kp/VII/1994. As a center of development in medical microbiology, Micro-UI has received competitive grants from World Bank, Ministry of Research and Technology,  Ministry of Health, the University of Indonesia, abroad such as International Atomic Energy Agency, KNCV, and National Institute for Infectious Diseases Japan. Recently, Micro-UI has been appointed as National Centre for Tuberculosis Research. The current research activities are focused on five subjects which Micro-UI excels in : Dengue Haemorrhagic fever, Tuberculosis, Antimicrobial Resistance, human immunodeficiency virus, and Sexually Transmitted Diseases. Projects apart from the main ones also encouraged and being developed.